The focus of this research is on the function of the holiday Purim in bath toys the life of Belgrade Jewish community.In diachronic perspective we are looking at general and local characteristics of the holiday, and different levels of its celebration (private, public sphere).In the studied community this holiday has undergone a transformation from
Probing Conformational States of a Target Protein in Escherichia coli Cells by in vivo Cysteine Cross-linking Coupled with Proteolytic Gel Analysis
Transporters are dynamic membrane proteins that are essential to the physiology of cells.To function, transporters must cycle between various conformational states, so to understand their mechanistic details, it is critical to characterize how their structure changes during the transport cycle.One approach to studying the dynamics of transporters t
Design and optimization of hollow microneedle spacing for three materials using finite element methods
Abstract The main advantages of microneedles are precise drug delivery through human skin, minimal tissue damage and painlessness.We conducted structural analysis and skin puncture studies of hollow microneedles using ANSYS for three materials: Hafnium Dioxide (HfO2), Polyglycolic acid (PGA) and Polylactic acid (PLA).Firstly, we selected three leng
Emerging Roles of cGAS-STING Signaling in Mediating Ocular Inflammation
Cyclic GMP-AMP (cGAMP) synthase (cGAS), a sensor of cytosolic DNA, recognizes cytoplasmic nucleic acids to activate the innate immune responses via generation of the second messenger cGAMP and subsequent activation of the stimulator of interferon genes (STINGs).The cGAS-STING signaling has multiple immunologic and physiological functions in all hum
Deadlock-Guided Testing
Static deadlock analyses might be able to verify the absence of deadlock.However, they are usually not Drum Stick Bag able to detect its presence.Moreover, when a potential deadlock is detected, they provide little (and often no) information that can help the user in finding the source of the anomalous behaviour.This paper proposes a testing method